An innovative project aspires to create a Human Cell Atlas in order to bring forward medical research and medical caretaking. The goal is for the Atlas to include a detailed description and characterization of all human cells in their healthy state.
The notion was presented in a conference in the presence of scientist and researches by Broad Institute of MIT and Harvard, Welcome trust and Sanger Institute.
The concept is to provide access to cell information for anyone who needs it, and enable research facilities helpful tools for their important work of finding cure or prevention for diseases such as cancer, Alzheimer and asthma.
The Atlas will show maps of cells, their locations in the body, the genes they express, and bring forward the understanding of cell activity and biological connections that direct and motivate activity.
New tools and technology such as single cell genomics may make cell mapping closer to realization. The Atlas could categorize cells to types and subtypes, location, cell situations, cell origin and more.
How can the Atlas influence the world of pathological diagnosis?
Cell Atlases have been used by pathologists for years and constitute the foundation of diagnosis. Understanding cell state and abnormal cells are critical for deciding upon courses of action when dealing with patients. New tools that can make diagnosis more specific and accurate are welcome. The field of pathology, though very senior, is always looking forward to improve the ability to prevent development of diseases, such as early detection of cancer, and progression of existing illness. Molecular pathology also uses gene sequencing and mapping to develop personalized medicine (PM). HPV detection, MSI test, Prosigna- a genomic test for classification and identification of breast cancer tumors, are some of the tests performed in L.E.M lab.